منابع مشابه
How to make spinal motor neurons.
All muscle movements, including breathing, walking, and fine motor skills rely on the function of the spinal motor neuron to transmit signals from the brain to individual muscle groups. Loss of spinal motor neuron function underlies several neurological disorders for which treatment has been hampered by the inability to obtain sufficient quantities of primary motor neurons to perform mechanisti...
متن کاملHow to make striatal projection neurons
Medium spiny neurons (MSNs) are the main projection neurons of the striatum and are preferentially lost in Huntington's disease (HD). With no current cure for this neurodegenerative disorder, the specificity of neuronal loss in the striatum makes cell transplantation therapy an attractive avenue for its treatment. Also, given that MSNs are particularly vulnerable in HD, it is necessary to under...
متن کاملHow Many Neurons Does it Take to Make a Mind?
The human race has made great strides in understanding the world around us, but the understanding of why it is we understand eludes us! We know that thought originates in the brain, we know that the brain is a network of billions of cells called neurons, we know that neurons transmit electric signals between one another and we even know how they transmit these signals, but we still do not know ...
متن کاملExperience-Dependent Development of Spinal Motor Neurons
Locomotor activity in many species undergoes pronounced alterations in early postnatal life, and environmental cues may be responsible for modifying this process. To determine how these events are reflected in the nervous system, we studied rats reared under two different conditions-the presence or absence of gravity-in which the performance of motor operations differed. We found a significant ...
متن کاملPurification and culture of spinal motor neurons.
Motor neurons are responsible for voluntary movement. Lower motor neurons are characterized by large soma, the potential to form very long axons, and wide-ranging dendritic arborization. They receive direction from various neuronal cell types and induce movement of skeletal muscle fibers through acetylcholine release at the neuromuscular junction. Each lower motor neuron can communicate with 10...
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ژورنال
عنوان ژورنال: Development
سال: 2014
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.097410